Since the International Association of Probiotics and Prebiotics (ISAPP) first released a consensus statement on prebiotics globally in 2021, the research on prebiotics in the domestic academic community has become increasingly popular, and the industry is also competing to layout prebiotics products. The development of the prebiotics industry has reached a critical period.

However, the concept of post emergence is not just a new one, but requires technological innovation support in various aspects such as strain screening, research and development preparation, and efficacy evaluation, making it a complete 'high-tech'. Therefore, the scientific research and business communities should enhance their sense of responsibility and jointly care for the healthy, regulated, and healthy development of the emerging industry of "emerging elements", and promote the high-quality development of the emerging element industry.

As a leader in the development of China's emerging metaindustry, Qingdao Yuanda Biotechnology Co., Ltd. adheres to its responsibility and mission, insists on technological innovation, cultivates the foundation of the development of the emerging metaindustry, and deeply cultivates the innovation and application of the emerging metaindustry. Through multiple tangible "emerging metatechnology achievements", it continuously enhances the "technological core" that leads the high-quality development of China's emerging metaindustry!

Develop China's first standard for emerging metagenomic groups

On February 21, 2023, the promotion meeting for the first domestic standard for post microbial products, "Probiotic and Lactic Acid Bacteria Post Microbial Products", led by Beijing Ketao Biotechnology and drafted by Qingdao Yuanda Biotechnology, was held in Beijing. Several authoritative experts and mainstream media witnessed the healthy development of China's post microbial industry reaching a new level.

It is reported that the standard was officially released and implemented by the China Bio Fermentation Industry Association on January 9th. Qingdao Yuanda Biotechnology Co., Ltd. participated in the entire process of standard establishment, drafting, modification, and approval, and contributed solid strength to the formulation of the standard and the development of the post fermentation industry with its industry advantages in the field of post fermentation.

This standard is mainly applicable to the production, inspection, and sales of probiotics derived from lactic acid bacteria. As the first group standard in the field of metagenomics in China, the release of this standard fills the gap of no standard for the development of metagenomics industry in China. In the future, it will vigorously promote the high-quality development of metagenomics industry in China!

In the group standard of "Probiotic Products Lactic Acid Bacteria Postbiotics", the term "Postbiotics" is defined for the first time as: products containing inactivated microorganisms and/or bacterial components with a clear genetic background that are beneficial to the health of the host, including or excluding their metabolites; Except for chemically synthesized components and viruses/bacteriophages and their products.

Simply put, retrobiotics are a collective term for beneficial components of probiotics that have been inactivated and processed. Compared to traditional active probiotics, retrobiotics have no limitations in activity and retain a large amount of nutrients and effective ingredients (such as vitamins, lipids, proteins, polysaccharides, organic acids, bacterial components, etc.).

The release and implementation of the standards for post production elements are of great significance for regulating the development of the post production element industry and promoting its healthy growth. One of them is to standardize the definition and scope of post fermentation elements, eliminate the ambiguity that some fermented foods are also post fermentation elements, and especially eliminate a large number of "counterfeit products" that promote the concept of stir frying and hype.

Postnatal Yuan's technological achievements have been rated as "internationally leading" level

Yuanda Biotechnology adheres to technological innovation and has achieved remarkable results in scientific research.

On February 10, 2023, the Qingdao Food Science and Technology Society organized a meeting with seven top experts in the industry, including academicians, at Qingdao Agricultural University to conduct an achievement appraisal. The scientific research achievement "Key Technologies and Applications for the Preparation of High Concentration Compound Probiotics and Their Metabolites (Epibiotics)" jointly completed by Qingdao Yuanda Biotechnology Co., Ltd., Qingdao Agricultural University, and Qingdao Special Food Research Institute passed the achievement appraisal smoothly. With unanimous agreement from experts, the achievement has reached the "international leading" level! The attending experts highly appreciate the results of the project and believe that the project has significant industrial application value, and should "further promote industrial application and achieve resource utilization".

This is the first time that the field of endogenous cells in China has received the highest international evaluation, which means that this technological achievement is the most advanced in the preparation and application of endogenous cells in contemporary times, far exceeding similar technologies at home and abroad. Yuanda Biotechnology, with its technological innovation capabilities and profound scientific research accumulation, has once again taken the lead in the world!

Convene the First China Postnatal Metatechnology Conference

As a leader in China's emerging metaindustry, Yuanda Biotechnology shoulders the mission and responsibility of promoting the healthy development of the metaindustry. In August 2022, Yuanda Biotechnology, as the initiator, successfully held the first China Postbiotics Science and Technology Conference in Qingdao in collaboration with the Key Laboratory of Dairy Biotechnology and Engineering of Inner Mongolia Agricultural University, the National Functional Food Engineering Technology Research Center of Jiangnan University, Qingdao Special Food Research Institute, and other units. More than 20 experts including academicians, national outstanding youth, Changjiang Scholars, and national outstanding youth, as well as nearly 100 industry leading enterprises, participated. The conference focused on academic reports and summit forums on cutting-edge achievements in the field of "Definition and Scope of Postbiotics" and "Evaluation and Mechanism of Postbiotics Efficacy", providing strong technological support for the industrial application of Postbiotics and firm confidence for the industrial layout of Postbiotics! The conference established the China Postbiotics Industry Development Community and the Postbiotics Industry Community Expert Committee, which played a positive role in promoting the research and industrial application of Postbiotics, and promoting the integrated development between the supply and demand sides of Postbiotics.

Building China's first metagenomic screening strain resource library

Postbiotics is not a tree without roots. Without a resource rich library of lactic acid bacteria strains, the screening and preparation of Postbiotics cannot be carried out, and industrialization cannot be discussed. Therefore, Yuanda Biotechnology firmly grasps the key of the strain resource library. Under the leadership of Chief Scientist Dr. Peng Chuantao, Yuanda Biotechnology has built the first targeted functional epigenetic strain resource library in China. The research team screened bacterial strains from traditional fermented foods, plants, traditional Chinese medicinal materials, and other resources with specific effects, and conducted extensive in vitro experiments, safety assessments, animal experiments, and human clinical trials to provide the core technology source for industrial production of targeted functional extracellular vesicles. At present, there are over 3000 strains of bacterial strains in the collection, and it is expected that there will be over 5000 strains of metabacterial strains after 2023.

Develop multiple epigenetic products based on scientific evidence and clinical trial evaluation

Yuanda Biotechnology attaches great importance to technological innovation, and its research team consists of more than 20 doctoral, postdoctoral, and master's degree holders from related majors. It has established a fully functional research and development laboratory and co built the "Probiotics and Postbiotics Basic Research and Development Application Innovation Platform" with Qingdao Agricultural University. At the same time, it has established long-term cooperation with well-known domestic and foreign research institutions such as the University of Copenhagen in Denmark, the Key Laboratory of Dairy Biotechnology and Engineering of Inner Mongolia Agricultural University, the Key Laboratory of Special Food Processing of the Ministry of Agriculture and Rural Affairs of Qingdao Agricultural University, the Qingdao Special Food Research Institute, and the Shandong Special Food Technology Innovation Center, and carefully studied the development of Postbiotics.

Through years of deep cultivation and accumulation, the company currently has five major emerging raw material products under its development:

1. Functional food ingredient - PostbioP ™- 6. Regulate gut microbiota, protect intestinal health, and enhance human immunity;

2. Patent skincare ingredient - Bilantera ®， Can enhance the skin barrier and consolidate the immune system of the largest organ in the human body - the skin;

3. Responsible for oral antibacterial raw materials - PostbioMT ™； Efficient inhibition and killing of oral pathogenic bacteria to maintain oral health;

4. Protecting Pet Health Raw Materials - PostbioA ™- 6. Solve multiple health problems such as constipation, diarrhea, and obesity in pets;

5. Natural anti-corrosion raw material - PostbioYDFF ™- 3. Inhibit various spoilage and pathogenic bacteria, truly achieving natural, green, and preservative properties.

Among them, the skincare ingredient Bilantera ® As a beneficial health factor for the skin, it is rich in antibacterial active ingredients such as antimicrobial peptides and short chain fatty acids, which can balance the microbiota and improve skin oiliness, sensitivity, inflammation, pigment deposition, and acne. Anti corrosion material PostbioYDFF ™- 3. It has the triple effects of biological preservation, immune enhancement, and improvement of digestive health. It can not only preserve and preserve various products such as food, but also regulate the balance of intestinal flora and assist in the treatment of gastrointestinal diseases.

While developing raw materials for post production, Yuanda Biotechnology also actively expands into the terminal product market, such as adding Bilantera ® The "Houshengyuan" skin care facial mask has passed the test of nearly 1000 people, and has remarkable effects of protecting skin barrier, removing acne, anti inflammation, anti allergy, regulating water oil balance, etc; Add PostbioMT ™ Children's toothpaste can inhibit various oral pathogenic bacteria, effectively prevent oral diseases such as dental caries and plaque, and protect children's oral health.

In the future, Yuanda Biology, as the "industry pioneer", will continue to deepen the scientific and technological innovation of the Youngster, ensure the cutting-edge and progressiveness of the related products of the Youngster, and build a leading brand of the Youngster with the help of strong research and development capabilities, modern production facilities, exquisite production technology, advanced quality control facilities, and strict quality control processes! At the same time, Yuanda will continue to develop and produce raw materials and functional terminal products for post production, leading the research and industrial application of post production technology in China, and promoting the rapid development of the post production market in China!